Anti-SPATA20抗體,精子發(fā)生相關(guān)蛋白20抗體產(chǎn)品介紹：SPATA20 is a 786 amino acid protein that may be involved in fertility regulation. SPATA20 is expressed in testis in an age dependent manner and localizes to round and elongated spermatids. SPATA20 contains a conserved thioredoxin-like domain near the N-terminus region and exists as four isoforms produced by alternative splicing events. SPATA20 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

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保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
連續(xù)使用時(shí)4°C存儲(chǔ)，保質(zhì)期六個(gè)月，*存儲(chǔ)時(shí)建議分裝為10ul以上小包裝-20°C存儲(chǔ)，并避免反復(fù)凍融，保質(zhì)期一年。

產(chǎn)品名稱 Anti-SPATA20抗體,精子發(fā)生相關(guān)蛋白20抗體

產(chǎn)品編號(hào) BYK-17625R

英文名稱 SPATA20
中文名稱 精子發(fā)生相關(guān)蛋白20抗體
別    名 SPATA20; Sperm protein SSP411; Sperm-specific protein 411; Spermatogenesis associated 20; Spermatogenesis-associated protein 20; SPT20_HUMAN; Ssp411; Tisp78; Transcript increased in spermiogenesis 78.
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  干細(xì)胞          

抗體來源 Rabbit or Mouse
克隆類型 Polyclonal or Monoclonal
交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請(qǐng)）

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