富含*重復(fù)蛋白8D抗體，LRRC8D抗體簡(jiǎn)單介紹：

產(chǎn)品編號(hào)：BYK-18412R

英文名稱：Anti-LRRC8D
中文名稱：富含*重復(fù)蛋白8D抗體

別名：FLJ10470; FLJ20403; LRC8D_HUMAN; Leucine rich repeat containing 5; Leucine rich repeat containing 8 family member D; Leucine rich repeat containing protein 8D; LRRC 5; LRRC 8D; LRRC5.

背景介紹：LRRC8D contains 12 LRR (leucine-rich) repeats. The function of this protein is unknown.

Function:
Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8D constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity). Mediates the import of the antibiotic blasticidin-S into cell (PubMed:24782309).

產(chǎn)品規(guī)格：50ul；100ul；200ul；1ml，*

抗體來(lái)源 Rabbit or Mouse

克隆類型 Polyclonal or Monoclonal

交叉反應(yīng)、產(chǎn)品應(yīng)用 （具體交叉反應(yīng)與產(chǎn)品應(yīng)用請(qǐng)或添加客服直接索?。?/span>

性    狀 Lyophilized or Liquid
濃    度 1mg/ml

富含*重復(fù)蛋白8D抗體，LRRC8D抗體產(chǎn)品信息：

設(shè)置對(duì)照

其目的在于證明和肯定陽(yáng)性結(jié)果的特異性，排除非特異性疑問(wèn)。主要是針對(duì)*抗體對(duì)照，常用的對(duì)照方法包括：1. 陽(yáng)性對(duì)照；2. 陰性對(duì)照；3. 阻斷實(shí)驗(yàn)； 4.替代對(duì)照；5. 空白對(duì)照；6. 自身對(duì)照；7. 吸收實(shí)驗(yàn).

1. 陽(yáng)性對(duì)照用已知抗原陽(yáng)性的切片作對(duì)照與待檢標(biāo)本同時(shí)進(jìn)行免疫組織化學(xué)染色，對(duì)照切片應(yīng)呈陽(yáng)性結(jié)果，成為陽(yáng)性對(duì)照。證明全過(guò)程均符合要求，尤其當(dāng)待檢標(biāo)本呈現(xiàn)陰性結(jié)果時(shí)，陽(yáng)性對(duì)照尤為重要。

2.陰性對(duì)照用確證不含已知抗原的標(biāo)本作對(duì)照，應(yīng)呈陰性結(jié)果，成為陰性對(duì)照，是陰性對(duì)照的一種。其實(shí)空白、替代、吸收和抑制都屬于陰性對(duì)照。當(dāng)待檢標(biāo)本呈陽(yáng)性結(jié)果時(shí)，陰性對(duì)照就更加重要，用以排除假陽(yáng)性。

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